Last Updated:30th January 2017

Nishida's Scopus
h-index=39, 4102 total citations
Nishida's Orchid

Go to Reviews etc.






  • Kishi, K., Onuma, TA, and Nishida, H.
  • Long-distance cell migration during larval development in the appendicularian, Oikopleura dioica.
  • Dev Biol.(2014) 395(2):299-306.

  • Kuwajima, M., Kumano, G., and Nishida, H.
  • Regulation of the number of cell division rounds by tissue-specific transcription factors and Cdk inhibitor during ascidian embryogenesis.
  • PLOS ONE(2014) 9, e90188. doi:10.1371/journal.pone.0090188.

  • Kumano, G., Negoro, N., and Nishida, H.
  • Transcription factor Tbx6 plays a central role in fate determination between mesenchyme and muscle in embryos of the ascidian, Halocynthia roretzi.
  • Dev. Growth Differ. (2014)56, 310-322.








  • Negishi T, Takada T, Kawai N, Nishida H. (2007).
  • Localized PEM mRNA and Protein Are Involved in Cleavage-Plane Orientation and Unequal Cell Divisions in Ascidians.
  • Current Biology 17, 1014-1025.

  • Tokuoka M, Kumano G, Nishida H. (2007).
  • FGF9/16/20 and Wnt-5alpha signals are involved in specification of secondary muscle fate in embryos of the ascidian, Halocynthia roretzi.
  • Development, Genes and Evolution 217, 515-527.

  • Kawai N, Iida Y, Kumano G, Nishida H. (2007).
  • Nuclear accumulation of beta-catenin and transcription of downstream genes are regulated by zygotic Wnt5alpha and maternal Dsh in ascidian embryos.
  • Developmental Dynamics 236, 1570-1582.

  • Matsumoto J, Kumano G, Nishida H. (2007).
  • Direct activation by Ets and Zic is required for initial expression of the Brachyury gene in the ascidian notochord.
  • Developmental Biology 306, 870-882.

  • Kim GJ, Kumano G, Nishida H. (2007).
  • Cell fate polarization in ascidian mesenchyme/muscle precursors by directed FGF signaling and role for an additional ectodermal FGF antagonizing signal in notochord/nerve cord precursors.
  • Development 134, 1509-1518.

  • Miyazaki, Y., Nishida, H. and Kumano, G. (2007).
  • Brain induction in ascidian embryos is dependent on juxtaposition of FGF9/16/20-producing and -receiving cells.
  • Development, Genes and Evolution 217, 177-188.



  • Nakamura Y, Makabe KW, Nishida H
  • POPK-1/Sad-1 kinase is required for the proper translocation of maternal mRNAs and putative germ plasm at the posterior pole of the ascidian embryo.
  • Development. 2005 Nov;132(21):4731-42.

  • Nishida H.
  • Specification of embryonic axis and mosaic development in ascidians.
  • Developmental Dynamics. 2005 Aug;233(4):1177-93. Review.

  • Sawada K, Fukushima Y, Nishida H
  • Macho-1 functions as transcriptional activator for muscle formation in embryos of the ascidian Halocynthia roretzi.
  • Gene Expression Patterns. 2005 Feb;5(3):429-37.

  • Kawai N, Takahashi H, Nishida H, Yokosawa H
  • Regulation of NF-κB/Rel by IκB is essential for ascidian notochord formation.
  • Developmental Biology. 2005 Jan 1;277(1):80-91.


  • Kazuto Taniguchi and Hiroki Nishida
  • Tracing cell fate in brain formation during embryogenesis of the ascidian Halocynthia roretzi.
  • Development Growth and Differentiation (2004) 46, 163-180.

  • Takashi Akanuma and Hiroki Nishida
  • Ets-mediated brain induction in embryos of the ascidian, Halocynthia roretzi.
  • Development, Genes and Evolution (2004) 214, 1-9.







  • Kim, G-J. and Nishida, H.
  • Monoclonal antibodies against differentiating mesenchyme cells in larvae of the ascidian, Halocynthia roretzi
  • Zool. Sci. 15, 553-559

  • Kumano, G. and Nishida, H.
  • Maternal and Zygotic Expression of the Endoderm-Specific Alkaline Phosphatase Gene in Embryos of the Ascidian, Halocynthia roretzi
  • Dev. Biol. 198, 245-252

  • Bates, W. R. and Nishida, H.
  • Developmental Roles of Nuclear Complex Factors Released During Oocyte Maturation in the Ascidians Halocynthia roretzi and Boltenia villosa
  • Zool. Sci. 15, 59-66

  • Hibino, T., Nishikata, T. and Nishida, H.
  • CAB(Centrosome-attracting body): A novel structure closely related to unequal cleavages in the ascidian embryo
  • Dev. Growth Differ. 40, 85-95


  • Hirano, T. and Nishida, H.
  • Developmental fates of larval tissues after metamorphosis in ascidian, Halocynthia roretzi
  • I. Origin of mesodermal tissues of the juvenile
  • Dev. Biol. 192, 199-210

  • Nakatani, Y. and Nishida, H.
  • Ras is an essential component for notochord formation during ascidian embryogenesis
  • Mech. Dev. 68, 81-89

  • Hori, S., Saitoh, T., Matsumoto, M., Makabe, K. W. and Nishida, H.
  • A Notch homologue from Halocynthia roretzi is preferentially expressed in the central nervous system during ascidian embryogenesis
  • Dev. Genes Evol. 207, 371-380

  • Nishida, H. and Kumano, G.
  • Analysis of temporal expression of endoderm-specific alkaline phosphatase during development of the ascidian, Halocynthia roretzi
  • Dev. Growth Differ. 39, 199-203

  • Kawaminami, S. and Nishida, H.
  • Induction of trunk lateral cells, the blood cell precursors, during ascidian embryogenesis
  • Dev. Biol. 181, 14-20


  • Yamada, A. and Nishida, H.
  • Distribution of cytoplasmic determinants in unfertilized eggs of the ascidian Halocynthia roretzi
  • Dev. Genes Evol. 206, 297-304

  • Kumano, G., Yokosawa, H. and Nishida, H.
  • Biochemical evidence for membrane-bound endoderm-specific alkaline phosphatase in larvae of the ascidian, Halocynthia roretzi
  • Eur. J. Biochem. 240, 485-489

  • Nakatani, Y.,Yasuo, H., Satoh, N. and Nishida, H.
  • Basic fibroblast growth factor induces notochord formation and the expression of As-T, a Brachyury homolog, during ascidian embryogenesis
  • Development 122, 2023-2031

  • Nishida, H.
  • Vegetal egg cytoplasm promotes gastrulation and is responsible for specification of vegetal blastomeres in embryos of the ascidian Halocynthia roretzi
  • Development 122, 1271-1279



  • Nakatani, Y. and Nishida, H.
  • Induction of notochord during ascidian embryogenesis
  • Dev. Biol. 166, 289-299

  • Nishida, H.
  • Localization of determinants for formation of the anterior-posterior axis in eggs of the ascidian Halocynthia roretzi
  • Development 120, 3093-3104

  • Nishida, H.
  • Localization of egg cytoplasm that promotes differentiation to epidermis in embryos of the ascidian Halocynthia roretzi
  • Development 120, 235-243


  • Nishida, H.
  • Localized regions of egg cytoplasm that promote expression of endoderm-specific alkaline phasphatase in embryos of ascidian Halocynthia roretzi
  • Development 118, 1-7


  • Nishida, H.
  • Regionality of egg cytoplasm that promotes muscle differentiation in ascidian, Halocynthia roretzi
  • Development 116, 521-529

  • Nishida, H.
  • Developmental potential for tissue differentiation of fully dissociated cells of the ascidian embryos
  • Roux's Arch. Dev. Biol. 201, 81-87


  • Nishida, H.
  • Induction of brain and sensory pigment cells in the ascidian embryo analyzed by experiments with isolate blastomeres
  • Development 112, 389-395


  • Nishida, H.
  • Determinative mechanisms in secondary muscle lineages of ascidian embryos: development of muscle-specific features in isolated muscle progenitor cells
  • Development 108, 559-568

Reviews etc.

  • Yamada, A., and Nishida, H.
    Control of the number of cell division rounds in distinct tissues during ascidian embryogenesis.
    Dev. Growth Differ. (2014) 56(5):376-86.

    Nishida, H and Stach, T.
    Cell lineages and fate maps in tunicates: Conservation and modification.
    Zool. Sci. (2014) 31(10):645-52.

    Nishida, H.
    The maternal muscle determinant in the ascidian egg.
    WIREs Dev. Biol. (2012). 1, 425-433.

    Makabe, K., and Nishida, H.
    Cytoplasmic localization and reorganization in ascidian eggs: Role of postplasmic/PEM RNAs in axis formation and fate determination.
    WIREs Dev. Biol.(2012). 1, 501-518.

    Polarizing animal cells via mRNA localization in oogenesis and early development.
    Dev. Growth Differ.(2011) 54, 1-18.

    Nishida, H., Satoh, N., and Hirose, E.
    More diversity and more convergence in tunicate biology.
    Zool. Sci.(2010) 27, 67-68.

    Sardet, C., Swalla, B. J., Satoh, N., Sasakura, Y., Branno, M., Thompson, E. M., Levine, M., and Nishida, H.
    Meeting review. Euro chordates: Ascidian community swims ahead.
    Dev. Dynam.(2008) 237, 1207-1213.

    Nishida, H.
    Development of the appendicularian Oikopleura dioica: culture, genome, and cell lineages.
    Dev. Growth Differ. (2008) 50, S239-S256.

    Lemaire, P., Smith, W. C., and Nishida, H.
    Ascidians and the plasticity of the chordate developmental program.
    Curr. Biol.(2008) 18, R620-R631.

  • Kumano G, Nishida H.
  • Ascidian embryonic development: An emerging model system for the study of cell fate specification in chordates.
  • Developmental Dynamics(2007). 236, 1732-1747.

  • Nishida H
  • Review: Specification of embryonic axis and mosaic development in ascidians.
  • Dev Dyn. (2005) Aug;233(4):1177-93.

  • Nishida, H.
  • Review: The zoological society prize: Analysis of cell fate specification during ascidian early embryogenesis
  • Zool. Sci. 20:1495-1496 (2003)

  • Kumano, G. and Smith, W. C.
  • Revisions to the Xenopus gastrula fate map: implications for mesoderm induction and patterning.
  • Dev. Dyn. (2002). 225, 409-421.

  • Nishida, H.
  • Review: Patterning the marginal zone of early ascidian embryos: Localized maternal mRNA and inductive interactions
  • BioEssays 24:613-624 (2002)

  • Nishida, H.
  • Review: Specification of developmental fates in ascidian embryos: Recent advances in molecular approach to maternal determinants and signaling molecules
  • Int. Rev. Cytol. 217,227-76 (2002)

  • Nishida, H., Morokuma, J., Nishikata, T.
  • Review: Maternal cytoplasmic factors for generation of unequal cleavage patterns in animal embryos
  • Curr. Top. in Dev. Biol. 46, 1-37 (1999)

  • Nishida, H., Makabe, KW.
  • Proceeding: Maternal information and localized maternal mRNA in eggs and early embryos of the ascidian Halocynthia roretzi
  • Invert. Rep. and Dev. 36, 41-49 (1999)

  • Nishida, H.
  • Review: Cell lineage and timing of fate restriction, determination and gene expression in ascidian embryos
  • Seminars in Cell and Developmental Biology 8, 359-365 (1997)

  • Nishida, H.
  • Review: Cell-fate specification by localized cytoplasmic determinants and cell interactions in ascidian embryos
  • International Review of Cytology 176, 245-306 (1997)

  • Nishida, H.
  • Essay: Determination at the last cell cycle before fate restriction
  • Zool. Sci. 13, 15-20 (1996)

  • Nishida, H.
  • Review: Determination of developmental fates of blastomeres in ascidian embryos
  • Dev. Growth Differ. 34, 253-262 (1992)